Article
Increased burden of familial-associated early-onset cancer risk among minority Americans compared to non-Latino Whites.
eLife - 22 Jun 2021
Feng Qianxi, Nickels Eric, Muskens Ivo S, de Smith Adam J, Gauderman W James, Yee Amy C, Ricker Charite, Mack Thomas, Leavitt Andrew D, Godley Lucy A, Wiemels Joseph L
Abstract excerpt
Background: The role of race/ethnicity in genetic predisposition of early-onset cancers can be estimated by comparing family-based cancer concordance rates among ethnic groups. Methods: We used linked California health registries to evaluate the relative cancer risks for first-degree relatives of patients diagnosed between ages 0 and 26, and the relative risks of developing distinct second primary malignancies...
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