Article
The Macrophage Response Is Driven by Mesenchymal Stem Cell-Mediated Metabolic Reprogramming.
Frontiers in immunology - 1 Jan 2021
Luque-Campos Noymar, Bustamante-Barrientos Felipe A, Pradenas Carolina, García Cynthia, Araya María Jesús, Bohaud Candice, Contreras-López Rafael, Elizondo-Vega Roberto, Djouad Farida, Luz-Crawford Patricia, Vega-Letter Ana María
Abstract excerpt
Mesenchymal stem cells (MSCs) are multipotent adult stromal cells widely studied for their regenerative and immunomodulatory properties. They are capable of modulating macrophage plasticity depending on various microenvironmental signals. Current studies have shown that metabolic changes can also affect macrophage fate and function. Indeed, changes in the environment prompt phenotype change. Therefore, in this...
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