Article
Role of amylopectin synthesis in Toxoplasma gondii and its implication in vaccine development against toxoplasmosis.
Open biology - 1 Jun 2021
Lyu Congcong, Yang Xuke, Yang Jichao, Hou Lun, Zhou Yanqin, Zhao Junlong, Shen Bang
Abstract excerpt
Toxoplasma gondii is a ubiquitous pathogen infecting one-third of the global population. A significant fraction of toxoplasmosis cases is caused by reactivation of existing chronic infections. The encysted bradyzoites during chronic infection accumulate high levels of amylopectin that is barely present in fast-replicating tachyzoites. However, the physiological significance of amylopectin is not fully understood....
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