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Flagellum inheritance in Trypanosoma brucei requires a kinetoplastid-specific protein phosphatase

17 Apr 2018

Abstract excerpt

Trypanosoma brucei causes sleeping sickness in humans and nagana in cattle in sub-Saharan Africa and alternates between its mammalian hosts and its insect vector, the tsetse fly. T. brucei uses a flagellum for motility, cell division, and cell–cell communication. Proper positioning and attachment of the newly assembled flagellum rely on the faithful duplication and segregation of flagellum-associated cytoskeletal...

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PMID: 29666191
DOI: 10.1074/jbc.ra118.002106

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