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Article

An aurora kinase homologue is involved in regulating both mitosis and cytokinesis in Trypanosoma brucei.

The Journal of biological chemistry - 7 Apr 2006

Tu Xiaoming, Kumar Praveen, Li Ziyin, Wang Ching C

Abstract excerpt

The chromosomal passenger protein aurora kinases have been implicated in regulating chromosome segregation and cell division. Three aurora kinase homologues were identified (TbAUK1, -2 and -3) in the Trypanosome Genomic Data Base, and their expressions in the procyclic form of Trypanosoma brucei were knocked down individually by using the RNA interference technique. Only a knockdown of TbAUK1 arrested the cells...

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Source

Identifiers

PMID: 16436376
DOI: 10.1074/jbc.M511504200

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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