cagA gene EPIYA motif genetic characterization from Colombian Helicobacter pylori isolates: Standardization of a molecular test for rapid clinical laboratory detection.

doi:10.1371/journal.pone.0227275

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Article

cagA gene EPIYA motif genetic characterization from Colombian Helicobacter pylori isolates: Standardization of a molecular test for rapid clinical laboratory detection.

PloS one - 1 Jan 2020

Rodríguez Gómez Eliana Rocío, Otero Regino William, Monterrey Pedro A, Trespalacios Rangel Alba Alicia

Abstract excerpt

The aim of this work was to determine current cagA gene EPIYA motifs present in Colombian Helicobacter pylori isolates using a fast and reliable molecular test. DNA from eighty-five Helicobacter pylori-cagA positive strains were analyzed. Strains were obtained from patients diagnosed with functional dyspepsia at Clínica Fundadores in Bogotá. The 3' region of the cagA gene was amplified through conventional...

Topics

Adult
Aged
Amino Acid Motifs
Antigens, Bacterial
Bacterial Proteins
Colombia
DNA, Bacterial
Diagnostic Tests, Routine
Dyspepsia
Female
Genes, Bacterial

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Genotype

Helicobacter Infections

Helicobacter pylori

Humans

Male

Middle Aged

Polymerase Chain Reaction

Source

Open in PubMed Open full text

Identifiers

PMID: 31923209
DOI: 10.1371/journal.pone.0227275
PMCID: PMC6953880

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-31923209-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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