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Article

Eicosanoid profiling in patients with complete form of pachydermoperiostosis carrying SLCO2A1 mutations.

The Journal of dermatology - 1 Sept 2021

Oiwa Tomohiro, Ishibashi Mami, Okuno Toshiaki, Ohba Mai, Endo Yuichiro, Uozumi Ryuji, Ghazawi Feras M, Yoshida Kazue, Niizeki Hironori, Yokomizo Takehiko, Nomura Takashi, Kabashima Kenji

Abstract excerpt

Pachydermoperiostosis (PDP) is a genetic disease characterized by digital clubbing, periostosis, and pachydermia caused by mutated HPGD or SLCO2A1. Plasma prostaglandin (PG)E2 levels are increased in these patients. However, other eicosanoids have not been quantitated. We aimed to quantitate plasma eicosanoid levels in four patients carrying SLCO2A1 mutations by high-performance liquid chromatography-tandem mass...

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PMID: 34114674
DOI: 10.1111/1346-8138.16012

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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