Article
Expression profiling identifies responder and non-responder phenotypes to interferon-beta in multiple sclerosis.
Brain : a journal of neurology - 1 Jun 2003
Stürzebecher S, Wandinger K P, Rosenwald A, Sathyamoorthy M, Tzou A, Mattar P, Frank J A, Staudt L, Martin R, McFarland H F
Abstract excerpt
Autoimmune diseases such as multiple sclerosis are characterized by complex genetic traits and pathomechanisms that translate into clinical heterogeneity. This wide heterogeneity of multiple sclerosis as well as different biological responses to immunomodulatory drugs can be expected to contribute to differential treatment responses. Strategies that dissect the relationship between the treatment response and the...
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