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Human Kidney Spheroids and Monolayers Provide Insights into SARS-CoV-2 Renal Interactions

10 Jun 2021

Abstract excerpt

Significance Statement Coronavirus disease 2019 (COVID-19) commonly results in AKI, but it is unknown whether AKI in patients with COVID-19 stems from direct kidney infection or indirect mechanisms. The authors explored the effects of infection with the causative virus, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), both in monolayers of primary human kidney cells and in kidney spheroids, a...

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PMID: 34112705
DOI: 10.1681/asn.2020111546

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