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Kidney organoids reveal redundancy in viral entry pathways during ACE2-dependent SARS-CoV-2 infection

9 Feb 2024

Abstract excerpt

With a high incidence of acute kidney injury among hospitalized COVID-19 patients, considerable attention has been focussed on whether SARS-CoV-2 specifically targets kidney cells to directly impact renal function, or whether renal damage is primarily an indirect outcome. To date, several studies have utilized kidney organoids to understand the pathogenesis of COVID-19, revealing the ability for SARS-CoV-2 to...

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PMID: 38334329
DOI: 10.1128/jvi.01802-23

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