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Article

A machine learning approach to screen for preclinical Alzheimer's disease.

Neurobiology of aging - 1 Sept 2021

Gaubert Sinead, Houot Marion, Raimondo Federico, Ansart Manon, Corsi Marie-Constance, Naccache Lionel, Sitt Jacobo Diego, Habert Marie-Odile, Dubois Bruno, De Vico Fallani Fabrizio, Durrleman Stanley, Epelbaum Stéphane

Abstract excerpt

Combining multimodal biomarkers could help in the early diagnosis of Alzheimer's disease (AD). We included 304 cognitively normal individuals from the INSIGHT-preAD cohort. Amyloid and neurodegeneration were assessed on 18F-florbetapir and 18F-fluorodeoxyglucose PET, respectively. We used a nested cross-validation approach with non-invasive features (electroencephalography [EEG], APOE4 genotype, demographic,...

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PMID: 34102381
DOI: 10.1016/j.neurobiolaging.2021.04.024

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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