Article
'You cannot expect miracles to happen overnight': patience pays off when you wish to establish a new adrenocortical carcinoma cell line.
European journal of endocrinology - 1 Jul 2021
Lalli Enzo
Abstract excerpt
Growing attention is being paid to the association of adrenocortical carcinoma (ACC), a rare endocrine malignancy, to cancer predisposition syndromes caused by germline mutations in genes involved in the control of genome stability. Tumour cells with a defective DNA mismatch repair pathway have a high mutation burden, which results in the production of tumour-associated specific neoantigens and in an increase of...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
