The Effect of the ABCB1(MDR-1) C3435T Polymorphism in Turkish Patients with Aspirin Resistance in Acute Ischemic Stroke.

doi:10.1007/s12975-023-01175-z

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The Effect of the ABCB1(MDR-1) C3435T Polymorphism in Turkish Patients with Aspirin Resistance in Acute Ischemic Stroke.

Translational stroke research - 1 Oct 2024

Yurek Emrah, Yavuz Burcu Genc, Tanoglu Esra Guzel, Gurkas Erdem, Altundag Ibrahim, Yalcinkaya Burhanettin, Yılmaz Erdal, Colak Sahin

Abstract excerpt

Recurrence of thrombotic events during aspirin therapy is known as aspirin resistance (AR). This study aimed to investigate the rate of AR, the factors influencing AR in patients with acute ischemic stroke under regular aspirin use, and the relationship between AR and ABCB1 (MDR-1) C3435T (rs1045642) polymorphism. Throughout this multicenter prospective study, 174 patients with acute ischemic stroke who had been...

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PMID: 37432593
DOI: 10.1007/s12975-023-01175-z

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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