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TaqMan real time PCR for the Detection of the Gilbert's Syndrome Markers UGT1A128; UGT1A136 and UGT1A1*37.

Molecular biology reports - 1 May 2021

Daprà Valentina, Alliaudi Carla, Galliano Ilaria, Dini Maddalena, Curcio Giada Lo, Calvi Cristina, Archetti Marialaura, Gavatorta Martina, Bergallo Massimiliano

Abstract excerpt

Gilbert's syndrome is characterized by mild unconjugated hyperbilirubinemia. The key of this disease is a diminished activity of UDP-glucuronosyltransferase 1A1 (UGT1A1). TA insertion into the TATA box promoter region of the UGT1A1 gene on chromosome 2 is the genetic basis of Gilbert's syndrome (UGT1A1*28). An extra TA insert leads to eight (TA)8 repeats (UGT1A1*37) resulting in a further reduction of...

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PMID: 34089128
DOI: 10.1007/s11033-021-06454-2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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