Article
SNPs at 3'UTR of APOL1 and miR-6741-3p target sites associated with kidney diseases more susceptible to SARS-COV-2 infection: in silco and in vitro studies.
Mammalian genome : official journal of the International Mammalian Genome Society - 1 Oct 2021
Safdar Muhammad, Khan Muhammad Sajjad, Karim Abdulkarim Yasin, Omar Shwan Ali, Smail Shukur Wasman, Saeed Muhammad, Zaheer Sana, Ali Mazhar, Ahmad Bilal, Tasleem Muhammad, Junejo Yasmeen
Abstract excerpt
Acute Kidney Injury (AKI) is a common manifestation of COVID-19 and several cases have been reported in the setting of the high-risk APOL1 genotype (common genetic variants). This increases the likelihood that African American people with the high-risk genotype APOL1 are at increased risk for kidney disease in the COVID-19 environment. Single-nucleotide polymorphisms (SNPs) are found in various microRNAs (miRNAs)...
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