Article
Molecular phenotyping and biomarker development: are we on our way towards targeted therapy for severe asthma?
Expert review of respiratory medicine - 1 Jan 2016
De Ferrari Laura, Chiappori Alessandra, Bagnasco Diego, Riccio Anna Maria, Passalacqua Giovanni, Canonica Giorgio Walter
Abstract excerpt
Although different phenotypes of severe asthma can be identified, all are characterized by common symptoms. Due to their heterogeneity, they exhibit differences in pathogenesis, etiology and clinical responses to therapeutic approaches. The identification of distinct molecular phenotypes to define severe asthmatic patients will allow us to better understand the pathophysiology of the disease and thus to more...
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