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Article

Whole-genome sequencing identifies functional noncoding variation in SEMA3C that cosegregates with dyslexia in a multigenerational family.

Human genetics - 1 Aug 2021

Carrion-Castillo Amaia, Estruch Sara B, Maassen Ben, Franke Barbara, Francks Clyde, Fisher Simon E

Abstract excerpt

Dyslexia is a common heritable developmental disorder involving impaired reading abilities. Its genetic underpinnings are thought to be complex and heterogeneous, involving common and rare genetic variation. Multigenerational families segregating apparent monogenic forms of language-related disorders can provide useful entrypoints into biological pathways. In the present study, we performed a genome-wide linkage...

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PMID: 34076780
DOI: 10.1007/s00439-021-02289-w
PMCID: PMC8263547

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