Recessive genomic and phenotypic variation in consanguineous families with cerebral palsy

Abstract excerpt

<h4>ABSTRACT</h4> Cerebral palsy (CP) is a neurodevelopmental disorder of motor function, with genetic etiologies, particularly de novo variants, identified in approximately one-third of cases. The contribution of consanguinity – long-recognized as a CP risk factor – has remained undefined. Here, we report findings from 188 primarily consanguineous Middle Eastern families with CP and identified putative causativ...

Topics

Open a Topic to create a Post that cites this publication.

• Cerebral Palsy
• Gene-Environment Interaction
• Genetic Predisposition to Disease
• Genetic Variation
• Infant, Newborn
• Pregnancy
• Risk Factors
• Sequence Analysis, DNA

Identifiers and source

Literature Corpus work

37ce6b50-f434-53e1-af59-d5e454710427

DOI

10.1101/2025.11.04.25339178