Article
The dysregulated Pink1- Drosophila mitochondrial proteome is partially corrected with exercise.
Aging - 1 Jun 2021
Ebanks Brad, Ingram Thomas L, Katyal Gunjan, Ingram John R, Moisoi Nicoleta, Chakrabarti Lisa
Abstract excerpt
One of the genes which has been linked to the onset of juvenile/early onset Parkinson's disease (PD) is PINK1. There is evidence that supports the therapeutic potential of exercise in the alleviation of PD symptoms. It is possible that exercise may enhance synaptic plasticity, protect against neuro-inflammation and modulate L-Dopa regulated signalling pathways. We explored the effects of exercise on Pink1...
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