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Article

Antitumor Effects of 5-Aminolevulinic Acid on Human Malignant Glioblastoma Cells

25 May 2021

Abstract excerpt

5-Aminolevulinic acid (5-ALA) is a naturally occurring non-proteinogenic amino acid, which contributes to the diagnosis and therapeutic approaches of various cancers, including glioblastoma (GBM). In the present study, we aimed to investigate whether 5-ALA exerted cytotoxic effects on GBM cells. We assessed cell viability, apoptosis rate, mRNA expressions of various apoptosis-related genes, generation of reactive...

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PMID: 34070493
DOI: 10.3390/ijms22115596

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