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Article

Methylation and Expression of FTO and PLAG1 Genes in Childhood Obesity: Insight into Anthropometric Parameters and Glucose-Lipid Metabolism.

Nutrients - 15 May 2021

Czogała Wojciech, Czogała Małgorzata, Strojny Wojciech, Wątor Gracjan, Wołkow Paweł, Wójcik Małgorzata, Bik Multanowski Mirosław, Tomasik Przemysław, Wędrychowicz Andrzej, Kowalczyk Wojciech, Miklusiak Karol, Łazarczyk Agnieszka, Hałubiec Przemysław, Skoczeń Szymon

Abstract excerpt

The occurrence of childhood obesity is influenced by both genetic and epigenetic factors. FTO (FTO alpha-ketoglutarate dependent dioxygenase) is a gene of well-established connection with adiposity, while a protooncogene PLAG1 (PLAG1 zinc finger) has been only recently linked to this condition. We performed a cross-sectional study on a cohort of 16 obese (aged 6.6-17.7) and 10 healthy (aged 11.4-16.9) children....

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Identifiers

PMID: 34063412
DOI: 10.3390/nu13051683
PMCID: PMC8155878

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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