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Co-expression gene network analysis reveals novel regulatory pathways involved in porto-sinusoidal vascular disease

28 May 2021

Abstract excerpt

BACKGROUND & AIMS: Porto-sinusoidal vascular disease (PSVD) is a rare vascular liver disease of unknown etiology that causes portal hypertension. It usually affects young individuals and shortens live expectancy. The deregulated pathways involved in PSVD development are unknown and therefore we lack curative treatments. The purpose of this study was to integrate transcriptomic and clinical data by comprehensive...

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PMID: 34052252
DOI: 10.1016/j.jhep.2021.05.014

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