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Human CD56+CD39+ dNK cells support fetal survival through controlling trophoblastic cell fate: immune mechanisms of recurrent early pregnancy loss

11 Apr 2024

Abstract excerpt

ABSTRACT Decidual natural killer (dNK) cells are the most abundant immune cells at the maternal-fetal interface during early pregnancy in both mice and humans, and emerging single-cell transcriptomic studies have uncovered various human dNK subsets that are disrupted in patients experiencing recurrent early pregnancy loss (RPL) at early gestational stage, suggesting a connection between abnormal proportions or...

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Share to Ectopic Pregnancy Diagnosis and Management
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PMID: 38966071
DOI: 10.1093/nsr/nwae142

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