Article
Cytokeratin-positive Malignant Tumor in the Abdomen With EWSR1/FUS-CREB Fusion: A Clinicopathologic Study of 8 Cases.
The American journal of surgical pathology - 1 Jan 2022
Shibayama Takahiro, Shimoi Tatsunori, Mori Taisuke, Noguchi Emi, Honma Yoshitaka, Hijioka Susumu, Yoshida Masayuki, Ogawa Chitose, Yonemori Kan, Yatabe Yasushi, Yoshida Akihiko
Abstract excerpt
ATF1, CREB1, and CREM, which encode the CREB family of transcription factors, are fused with EWSR1 or FUS in human neoplasms, such as angiomatoid fibrous histiocytoma. EWSR1/FUS-CREB fusions have recently been reported in a group of malignant epithelioid tumors with a predilection to the peritoneal cavity and frequent cytokeratin expression. Here, we studied 8 cytokeratin-positive abdominal malignancies with...
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