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Article

A group of sclerosing epithelioid fibrosarcomas with low-level amplified EWSR1-CREB3L1 fusion gene in children.

Pathology, research and practice - 1 Feb 2022

Zhang Meng, Yu Yongbo, Guan Xiaoxing, Yao Xingfeng, Jia Chao, Hong Enyu, Guo Yongli, He Lejian

Abstract excerpt

Sclerosing epithelioid fibrosarcoma (SEF), typically arising in middle-aged and older adults, is a rare malignant fibroblastic neoplasm characterized by epithelioid fibroblasts embedded in sclerotic hyalinized stroma. This tumor frequently harbors translocation between EWSR1 and CREB3 subfamily members. Here, we describe four cases of SEF with unique genetic characteristics in children. All tumors were located in...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 34990868
DOI: 10.1016/j.prp.2021.153754

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