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Article

Minor allele of rs55763075 located in MTHFR is associated with the risk of cognitive impairment after anesthesia via modulating miR-34b.

Scientific reports - 27 May 2021

Li Si-Ying, Lei He-Shou, Wu Xiao-Yun, Li Kai, Liu Zhi-Min, Lu Jian-Hui, Chen Xiao-Yun

Abstract excerpt

This study aimed to investigate the association between cognitive impairment after general anesthesia and rs55763075 polymorphisms. We enrolled and grouped patients undergoing general anesthesia according to their genotypes of rs55763075 polymorphism. Mini-Mental State Examination (MMSE) scoring was performed to evaluate the cognitive status of patients. Quantitative real-time PCR was carried out to analyze the...

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Source

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Identifiers

PMID: 34045473
DOI: 10.1038/s41598-021-90229-z
PMCID: PMC8159953

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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