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Article

Impacts of the SOAT1 genetic variants and protein expression on HBV-related hepatocellular carcinoma.

BMC cancer - 26 May 2021

Chen Yulong, Yang Xunjun, Chen Yao, Chen Guorong, Winkler Cheryl A, An Ping, Lyu Jianxin

Abstract excerpt

BACKGROUND: Hepatitis B virus (HBV)-related hepatocellular carcinoma (HCC) remains a major public health problem and its pathogenesis remains unresolved. A recent proteomics study discovered a lipid enzyme Sterol O-acyltransferase (SOAT1) involvement in the progression of HCC. We aimed to explore the association between SOAT1 genetic variation and HCC. METHODS: We genotyped three exonic SOAT1 variants...

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Identifiers

PMID: 34039309
DOI: 10.1186/s12885-021-08245-1
PMCID: PMC8152151

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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