Article
Virulence and live vaccine potential of Edwardsiella piscicida phoP and phoQ mutants in catfish against edwardsiellosis.
Journal of fish diseases - 1 Sept 2021
Sayed Mohamed, Ozdemir Ozan, Essa Manal, Olivier Alicia, Karsi Attila, Lawrence Mark L, Abdelhamed Hossam
Abstract excerpt
Edwardsiella piscicida is a Gram-negative facultative intracellular bacterium causing edwardsiellosis in catfish, the largest aquaculture industry in the United States. A safe and effective vaccine is an urgent need to avoid economic losses associated with E. piscicida outbreaks. PhoP/PhoQ is a two-component signal transduction system (TCS) that plays an important role in bacterial pathogenesis through sense and...
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