Article
The virulence and immune protection of Edwardsiella ictaluri HemR mutants in catfish.
Fish & shellfish immunology - 1 Jan 2018
Abdelhamed Hossam, Ibrahim Iman, Baumgartner Wes, Lawrence Mark L, Karsi Attila
Abstract excerpt
Edwardsiella ictaluri is a Gram-negative facultative intracellular rod, causing enteric septicemia of catfish (ESC). Several heme uptake systems have been described in bacterial pathogens, most of which involve outer membrane proteins (OMPs). We have shown recently that heme/hemoglobin receptor family protein (HemR) is significantly up-regulated in E. ictaluri under iron-restricted conditions. In this work, our...
Topics
- Animals
- Bacterial Outer Membrane Proteins
- Edwardsiella ictaluri
- Enterobacteriaceae Infections
- Fish Diseases
- Ictaluridae
- Mutation
- Random Allocation
- Receptors, Cell Surface
- Virulence