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Article

α-Tubulin Regulates the Fate of Germline Stem Cells in Drosophila Testis.

Scientific reports - 20 May 2021

Tao Xiaoqian, Dou Yunqiao, Huang Guangyu, Sun Mingzhong, Lu Shan, Chen Dongsheng

Abstract excerpt

The Drosophila testis provides an exemplary model for analyzing the extrinsic and intrinsic factors that regulate the fate of stem cell in vivo. Using this model, we show that the Drosophila αTub67C gene (full name αTubulin at 67C), which encodes α4-Tubulin (a type of α-Tubulin), plays a new role in controlling the fate of male germline stem cells (GSC). In this study, we have found that Drosophila α4-Tubulin is...

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Identifiers

PMID: 34017013
DOI: 10.1038/s41598-021-90116-7
PMCID: PMC8138004

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