Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Whole mitochondrial genome analysis in Chinese patients with keratoconus.

Molecular vision - 1 Jan 2021

Xu Liyan, Yang Kaili, Fan Qi, Zhao Dongqing, Pang Chenjiu, Ren Shengwei

Abstract excerpt

Purpose: Keratoconus (KC) is a corneal disorder characterized by corneal ectasia, progressive corneal thinning, and conical protrusion. This study aimed to elucidate the mitochondrial gene profile in Chinese patients with KC, analyze the mitochondrial haplogroup and heteroplasmy, and further explore the association between mitochondrial genes and KC. Methods: Mitochondrial sequencing was conducted on 100 patients...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Asian People
Share to China
Share to DNA, Mitochondrial

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Electron Transport Complex IV

Share to Genes, Mitochondrial

Share to Genome, Mitochondrial

Share to Keratoconus

Share to Young Adult

Source

Open in PubMed Open full text

Identifiers

PMID: 34012229
PMCID: PMC8116249

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Whole mitochondrial genome analysis in Chinese patients with keratoconus.PMID 34012229Read ↗

Trio-based whole-exome sequencing of 200 Chinese patients with keratoconus.Semantic proximity Read ↗

Novel mutations identified in the Chinese Han population with keratoconus by next-generation sequencingSemantic proximity Read ↗

Mitochondrial sequence changes in keratoconus patients.Semantic proximity Read ↗

Mitochondrial DNA copy number, but not haplogroup is associated with keratoconus in Han Chinese population.Semantic proximity Read ↗

Decreased Integrity, Content, and Increased Transcript Level of Mitochondrial DNA Are Associated with KeratoconusSemantic proximity Read ↗

Exome sequencing identification of susceptibility genes in Chinese patients with keratoconus.Semantic proximity Read ↗

Mitochondrial complex 1 gene analysis in keratoconus.Semantic proximity Read ↗

Association of Novel Loci With Keratoconus Susceptibility in a Chinese Genome-Wide Association Study.Semantic proximity Read ↗

A genetic investigation in five Chinese families with keratoconus.Semantic proximity Read ↗

Three novel variants identified within ECM-related genes in Chinese Han keratoconus patients.Semantic proximity Read ↗

Association of mitochondrial haplogroups H and R with keratoconus in Saudi Arabian patients.Semantic proximity Read ↗

Whole-exome sequencing screening for candidate genes and variants associated with primary sporadic keratoconus in Chinese patients.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.