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Article

Three novel variants identified within ECM-related genes in Chinese Han keratoconus patients.

Scientific reports - 3 Apr 2020

Xu Xiayan, Zhang Xin, Cui Yilei, Yang Hao, Ping Xiyuan, Wu Jing, Yu Xiaoning, Jin Xiuming, Huang Xiaodan, Shentu Xingchao

Abstract excerpt

As the primary indication for corneal transplantation, the pathogenesis of keratoconus remains elusive. Aiming to identify whether any mutation from extracellular-matrix (ECM)-related genes contributes to the patients with sporadic cases of keratoconus (KC) from Chinese Han population, one hundred and fifty-three participants in total were enrolled in our study, including fifty-three KC patients and one hundred...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 32246022
DOI: 10.1038/s41598-020-62572-0
PMCID: PMC7125089

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