Article
Whole-exome sequencing screening for candidate genes and variants associated with primary sporadic keratoconus in Chinese patients.
Experimental eye research - 1 Aug 2024
Song Chunyuan, Li Ling, Liu Chang, Hu Luping, Bai Jie, Liang Weiyan, Zhao Lin, Song Wenxiu, Li Shaowei
Abstract excerpt
The pathogenesis of keratoconus (KC) is complex, and genetic factors play an important role. The purpose of this study was to screen and analyse candidate genes and variants in Chinese patients with primary sporadic KC. Whole-exome sequencing (WES) was performed to identify candidate genes and variants in 105 unrelated Chinese patients with primary sporadic KC. Through a series of screening processes, 54...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.