Article
Mitochondrial complex 1 gene analysis in keratoconus.
Molecular vision - 1 Jan 2011
Pathak Dhananjay, Nayak Bhagabat, Singh Manvendra, Sharma Namrata, Tandon Radhika, Sinha Rajesh, Titiyal Jeewan S, Dada Rima
Abstract excerpt
PURPOSE: Keratoconus is characterized by the thinning of corneal stroma, resulting in reduced vision. The exact etiology of keratoconus (KC) is still unknown. The involvement of oxidative stress (OS) in this disease has been reported. However, the exact mechanism of OS in keratoconus is still unknown. Thus we planned this study to screen mitochondrial complex I genes for sequence changes in keratoconus patients...
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