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Mitotic checkpoint regulator RAE1 promotes tumor growth in colorectal cancer

18 May 2021

Abstract excerpt

Microtubules are among the most successful targets for anticancer therapy because they play important roles in cell proliferation as they constitute the mitotic spindle, which is critical for chromosome segregation during mitosis. Hence, identifying new therapeutic targets encoding proteins that regulate microtubule assembly and function specifically in cancer cells is critical. In the present study, we...

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PMID: 34008277
DOI: 10.1111/cas.14969

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