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Emerging concepts in PD-1 checkpoint biology

1 Feb 2021

Abstract excerpt

The PD-1 pathway is a cornerstone in immune regulation. While the PD-1 pathway has received considerable attention for its role in contributing to the maintenance of T cell exhaustion in chronic infection and cancer, the PD-1 pathway plays diverse roles in regulating host immunity beyond T cell exhaustion. Here, we discuss emerging concepts in the PD-1 pathway, including (1) the impact of PD-1 inhibitors on...

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PMID: 34006473
DOI: 10.1016/j.smim.2021.101480

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