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Identification of a DNA Methylation-Based Prognostic Signature for Patients with Triple-Negative Breast Cancer

1 Mar 2021

Abstract excerpt

BACKGROUND Aberrant DNA methylation is an important biological regulatory mechanism in malignant tumors. However, it remains underutilized for establishing prognostic models for triple-negative breast cancer (TNBC). MATERIAL AND METHODS Methylation data and expression data downloaded from The Cancer Genome Atlas (TCGA) were used to identify differentially methylated sites (DMSs). The prognosis-related DMSs were...

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PMID: 34003815
DOI: 10.12659/msm.930025

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