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Genome-wide DNA methylation profiling in triple-negative breast cancer reveals epigenetic signatures with important clinical value

26 May 2015

Abstract excerpt

Analysis of cancer methylomes has dramatically changed our concept of the potential of diagnostic and prognostic methylation biomarkers in disease stratification. Through whole-genome methylation capture sequencing of triple-negative breast cancers (TNBCs) we recently identified differentially methylated regions with diagnostic and prognostic value that promise to stratify TNBCs for more personalized management.

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Identifiers

PMID: 27308556
DOI: 10.1080/23723556.2015.1038424

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