Article
Cryo-EM structures of an insecticidal Bt toxin reveal its mechanism of action on the membrane.
Nature communications - 14 May 2021
Byrne Matthew J, Iadanza Matthew G, Perez Marcos Arribas, Maskell Daniel P, George Rachel M, Hesketh Emma L, Beales Paul A, Zack Marc D, Berry Colin, Thompson Rebecca F
Abstract excerpt
Insect pests are a major cause of crop losses worldwide, with an estimated economic cost of $470 billion annually. Biotechnological tools have been introduced to control such insects without the need for chemical pesticides; for instance, the development of transgenic plants harbouring genes encoding insecticidal proteins. The Vip3 (vegetative insecticidal protein 3) family proteins from Bacillus thuringiensis...
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