Article
3D facial phenotyping by biometric sibling matching used in contemporary genomic methodologies.
PLoS genetics - 1 May 2021
Hoskens Hanne, Liu Dongjing, Naqvi Sahin, Lee Myoung Keun, Eller Ryan J, Indencleef Karlijne, White Julie D, Li Jiarui, Larmuseau Maarten H D, Hens Greet, Wysocka Joanna, Walsh Susan, Richmond Stephen, Shriver Mark D, Shaffer John R, Peeters Hilde, Weinberg Seth M, Claes Peter
Abstract excerpt
The analysis of contemporary genomic data typically operates on one-dimensional phenotypic measurements (e.g. standing height). Here we report on a data-driven, family-informed strategy to facial phenotyping that searches for biologically relevant traits and reduces multivariate 3D facial shape variability into amendable univariate measurements, while preserving its structurally complex nature. We performed a...
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