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Host-Virus Chimeric Events in SARS-CoV-2-Infected Cells Are Infrequent and Artifactual

13 May 2021

Abstract excerpt

The pathogenic mechanisms underlying SARS-CoV-2, the virus responsible for COVID-19, are not fully understood. In particular, relatively little is known about the reasons some individuals develop life-threatening or persistent COVID-19. Recent studies identified host-virus chimeric (HVC) reads in RNA-sequencing data from SARS-CoV-2-infected cells and suggested that HVC events support potential "human genome...

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PMID: 33980601
DOI: 10.1128/jvi.00294-21

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