Article
Dysregulation of Rnf 213 gene contributes to T cell response via antigen uptake, processing, and presentation.
Journal of cellular physiology - 1 Nov 2021
Tashiro Ryosuke, Niizuma Kuniyasu, Kasamatsu Jun, Okuyama Yuko, Rashad Sherif, Kikuchi Atsuo, Fujimura Miki, Kure Shigeo, Ishii Naoto, Tominaga Teiji
Abstract excerpt
Growing evidence suggest the association between Moyamoya disease (MMD) and immune systems, such as antigen presenting cells in particular. Rnf213 gene, a susceptibility gene for MMD, is highly expressed in immune tissues, however, its function remains unclear. In addition, the physiological role of RNF213 gene polymorphism c.14576G > A (rs112735431), susceptibility variant for MMD, is also poorly understood. By...
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