Article
Increased serum production of soluble CD163 and CXCL5 in patients with moyamoya disease: Involvement of intrinsic immune reaction in its pathogenesis.
Brain research - 15 Jan 2018
Fujimura Miki, Fujimura Taku, Kakizaki Aya, Sato-Maeda Mika, Niizuma Kuniyasu, Tomata Yasutake, Aiba Setsuya, Tominaga Teiji
Abstract excerpt
Moyamoya disease (MMD) is a rare cerebrovascular disease characterized by a progressive stenosis at the terminal portion of the internal carotid artery and an abnormal vascular network at the base of the brain. Although its etiology is still unknown, intrinsic immune reactions such as autoimmune response has been implicated in the pathogenesis of MMD. Recently, the RING finger protein 213 (RNF213) was found to be...
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