Article
Precision medicine and precision therapeutics: hedgehog signaling pathway, basal cell carcinoma and beyond.
Seminars in cutaneous medicine and surgery - 1 Jun 2014
Mohan Shalini V, Chang Anne Lynn S
Abstract excerpt
Precision medicine and precision therapeutics is currently in its infancy with tremendous potential to improve patient care by better identifying individuals at risk for skin cancer and predict tumor responses to treatment. This review focuses on the Hedgehog signaling pathway, its critical role in the pathogenesis of basal cell carcinoma, and the emergence of targeted treatments for advanced basal cell...
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