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Article

Serum levels of the IgA isotype switch factor TGF-β1 are elevated in patients with COVID-19.

FEBS letters - 1 Jul 2021

Wang Er-Yi, Chen Hao, Sun Bao-Qing, Wang Hui, Qu Hui-Qi, Liu Yichuan, Sun Xi-Zhuo, Qu Jingchun, Fang Zhang-Fu, Tian Lifeng, Zeng Yi-Feng, Huang Shau-Ku, Hakonarson Hakon, Liu Zhi-Gang

Abstract excerpt

We previously observed enhanced immunoglobulin A (IgA) responses in severe COVID-19, which might confer damaging effects. Given the important role of IgA in immune and inflammatory responses, the aim of this study was to investigate the dynamic response of the IgA isotype switch factor TGF-β1 in COVID-19 patients. We observed, in a total of 153 COVID-19 patients, that the serum levels of TGF-β1 were increased...

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Identifiers

PMID: 33961290
DOI: 10.1002/1873-3468.14104
PMCID: PMC8209884

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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