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Article

IDH-mutant brainstem gliomas in adolescent and young adult patients: Report of three cases and review of the literature.

Brain pathology (Zurich, Switzerland) - 1 Jul 2021

Chang Ellen K, Smith-Cohn Matthew A, Tamrazi Benita, Ji Jianling, Krieger Mark, Holdhoff Matthias, Eberhart Charles G, Margol Ashley S, Cotter Jennifer A

Abstract excerpt

Isocitrate dehydrogenase (IDH) mutations are rare in pediatric and adolescent gliomas. We recently identified three adolescent/young adult (AYA) patients with IDH-mutant low grade gliomas of the brainstem with several key clinicopathologic and molecular features in common. We discuss these three cases and review the current literature.

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Identifiers

PMID: 33960568
DOI: 10.1111/bpa.12959
PMCID: PMC8412065

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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