Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Identification of neutrophil β2-integrin LFA-1 as a potential mechanistic biomarker in ANCA-associated vasculitis via microarray and validation analyses

6 May 2021

Abstract excerpt

BACKGROUND: Leukocyte activation by anti-neutrophil cytoplasmic antibody (ANCA) and the subsequent leukocyte-endothelium interaction play a key role in the development of endothelial damage in ANCA-associated vasculitis (AAV). In contrast to that of leukocyte activation, the exact role of the leukocyte-endothelium interaction via integrin remains unclear. Here, we performed microarray and validation analyses to...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Autoimmune and Inflammatory Disorders
Share to Neutrophil, Myeloperoxidase and Oxidative Mechanisms
Share to Vasculitis and related conditions

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 33957974
DOI: 10.1186/s13075-021-02510-1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Identification of neutrophil β2-integrin LFA-1 as a potential mechanistic biomarker in ANCA-associated vasculitis via microarray and validation analysesPMID 33957974Read ↗

Classification of ANCA-associated vasculitis: differences based on ANCA specificity and clinicopathologic phenotype.Semantic proximity Read ↗

Longitudinal monitoring of circulating immune cell phenotypes in anti-neutrophil cytoplasmic antibody-associated vasculitis.Semantic proximity Read ↗

The genomic landscape of ANCA-associated vasculitis: Distinct transcriptional signatures, molecular endotypes and comparison with systemic lupus erythematosusSemantic proximity Read ↗

Neutrophils and Platelets as Key Players in the Pathogenesis of ANCA-Associated Vasculitis and Potential Sources of Disease Activity BiomarkersSemantic proximity Read ↗

Antineutrophil cytoplasm antibody-associated vasculitis: recent developments.Semantic proximity Read ↗

Pathogenesis of ANCA-associated vasculitis.Semantic proximity Read ↗

Microarray Studies of Gene Expression in Circulating Leukocytes in Kidney DiseasesSemantic proximity Read ↗

Review article: Pathogenic role of complement activation in anti‐neutrophil cytoplasmic auto‐antibody‐associated vasculitisSemantic proximity Read ↗

Genetics of ANCA-associated Vasculitides.Semantic proximity Read ↗

Significant association between clinical characteristics and immuno-phenotypes in patients with ANCA-associated vasculitisSemantic proximity Read ↗

Cardiovascular risk in ANCA-associated vasculitis: monocyte phenotyping reveals distinctive signatures between serological subsetsSemantic proximity Read ↗

[Pathophysiology of ANCA-associated vasculitides].Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.