Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Overexpression of microRNA‑486 affects the proliferation and chemosensitivity of mesothelioma cell lines by targeting PIM1

28 Apr 2021

Abstract excerpt

Dysregulated levels of microRNAs (miRNAs or miRs), involved in oncogenic pathways, have been proposed to contribute to the aggressiveness of malignant pleural mesothelioma (MPM). Previous studies have highlighted the downregulation of miRNA miR‑486‑5p in patients with mesothelioma and the introduction of miRNA mimics to restore their reduced or absent functionality in cancer cells is considered an important...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer Mechanisms and Therapy
Share to Peptidase Inhibition and Analysis

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 33955505
DOI: 10.3892/ijmm.2021.4950

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Overexpression of microRNA‑486 affects the proliferation and chemosensitivity of mesothelioma cell lines by targeting PIM1PMID 33955505Read ↗

MicroRNA-215-5p Treatment Suppresses Mesothelioma Progression via the MDM2-p53-Signaling AxisSemantic proximity Read ↗

miR-1 Induces Growth Arrest and Apoptosis in Malignant MesotheliomaSemantic proximity Read ↗

microRNA-497-5p-based screening identifies a novel synthetic lethal-type interaction via PKMYT1 and WEE1 in pleural mesotheliomaSemantic proximity Read ↗

Role of microRNAs in malignant mesotheliomaSemantic proximity Read ↗

Impact of metallothionein-knockdown on cisplatin resistance in malignant pleural mesotheliomaSemantic proximity Read ↗

Manipulating microRNAs for the Treatment of Malignant Pleural Mesothelioma: Past, Present and FutureSemantic proximity Read ↗

P53-regulated miR-320a targets PDL1 and is downregulated in malignant mesotheliomaSemantic proximity Read ↗

Efficacy of CDK4/6 inhibitors in preclinical models of malignant pleural mesotheliomaSemantic proximity Read ↗

Mesothelial cell proliferation and apoptosisSemantic proximity Read ↗

miR-379/411 cluster regulates IL-18 and contributes to drug resistance in malignant pleural mesotheliomaSemantic proximity Read ↗

MicroRNAs Dysregulation in Human Malignant Pleural MesotheliomaSemantic proximity Read ↗

Critical review about MDM2 in cancer: Possible role in malignant mesothelioma and implications for treatmentSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.