Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

miR-379/411 cluster regulates IL-18 and contributes to drug resistance in malignant pleural mesothelioma

16 Sept 2014

Abstract excerpt

Malignant pleural mesothelioma (MPM) is a rapidly fatal malignancy that is increasing in incidence in Japan. In this study, we performed gene and microRNA (miRNA) expression profiling to identify novel therapeutic targets in MPM cells. Based on relative sensitivities to pemetrexed (PEM) and the histone deacetylase (HDAC) inhibitor, vorinostat (SAHA), 211H cells were determined to be the only sensitive MPM cell...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
Share to Medical Imaging and Pathology Studies
Share to Occupational and environmental lung diseases

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 25231602
DOI: 10.3892/or.2014.3481

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

miR-379/411 cluster regulates IL-18 and contributes to drug resistance in malignant pleural mesotheliomaPMID 25231602Read ↗

Overexpression of microRNA‑486 affects the proliferation and chemosensitivity of mesothelioma cell lines by targeting PIM1Semantic proximity Read ↗

Integrated Experimental and In-Silico Analysis Reveals Melittin as a Modulator of IL-37a-Associated Networks in NeuroblastomaSemantic proximity Read ↗

Genomic Instability and Protumoral Inflammation Are Associated with Primary Resistance to Anti–PD-1 + Antiangiogenesis in Malignant Pleural MesotheliomaSemantic proximity Read ↗

Deciphering signaling pathway interplay via miRNAs in malignant pleural mesotheliomaSemantic proximity Read ↗

Upregulation of Thymidylate Synthase Induces Pemetrexed Resistance in Malignant Pleural MesotheliomaSemantic proximity Read ↗

Inhibition of CDK4/6 Overcomes Primary Resistance to PD-1 Blockade in Malignant MesotheliomaSemantic proximity Read ↗

Efficacy of CDK4/6 inhibitors in preclinical models of malignant pleural mesotheliomaSemantic proximity Read ↗

P53-regulated miR-320a targets PDL1 and is downregulated in malignant mesotheliomaSemantic proximity Read ↗

IL-17/miR-192/IL-17Rs Regulatory Feedback Loop Facilitates Multiple Myeloma ProgressionSemantic proximity Read ↗

Preclinical evaluation of CDK4 phosphorylation predicts high sensitivity of malignant pleural mesotheliomas to CDK4/6 inhibitionSemantic proximity Read ↗

IL-10Rα expression is post-transcriptionally regulated by miR-15a, miR-185, and miR-211 in melanomaSemantic proximity Read ↗

Melodic maestros: Unraveling the role of miRNAs in the diagnosis, progression, and drug resistance of malignant pleural mesotheliomaSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.