Article
Analytical validation of GMEX rapid point-of-care CYP2C19 genotyping system for the CHANCE-2 trial.
Stroke and vascular neurology - 1 Jun 2021
Meng Xia, Wang Anxin, Zhang Guojun, Niu Siying, Li Wei, Han Sifei, Fang Fang, Zhao Xingquan, Dong Kehui, Jin Zening, Zheng Huaguang, Chen Kelin, Li Hao, Yang Chengyuan, Wang Yongjun
Abstract excerpt
BACKGROUND AND PURPOSE: Rapid genotyping is useful for guiding early antiplatelet therapy in patients with high-risk nondisabling ischaemic cerebrovascular events (HR-NICE). Conventional genetic testing methods used in CYP2C19 genotype-guided antiplatelet therapy for patients with HR-NICE did not satisfy the needs of the Clopidogrel in High-Risk Patients with Acute Nondisabling Cerebrovascular Events (CHANCE)-2...
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